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GLOSSARY

LDL Cholesterol (Low-Density Lipoprotein)

The 'bad' cholesterol that can build up in artery walls. Lower levels reduce cardiovascular disease risk.

What is LDL Cholesterol?

LDL (low-density lipoprotein) is often called "bad" cholesterol because it can deposit cholesterol in your artery walls, contributing to atherosclerosis — the buildup of fatty plaques that narrow arteries and increase heart attack and stroke risk.

Unlike HDL, which removes cholesterol, LDL delivers it to tissues, including places where it can cause harm.

Normal Ranges

LevelCategory
Below 100 mg/dLOptimal
100–129 mg/dLNear optimal
130–159 mg/dLBorderline high
160–189 mg/dLHigh
190+ mg/dLVery high

For people with heart disease or diabetes, targets are often lower (below 70 mg/dL).

Why It Matters

Primary Cardiovascular Risk Factor

LDL is the primary driver of atherosclerosis. Lowering LDL is one of the most evidence-backed ways to reduce heart disease risk.

Cumulative Exposure

Cardiovascular risk depends on lifetime LDL exposure. Lower levels earlier in life provide greater protection.

What Raises LDL

  • Saturated fat — Red meat, full-fat dairy, tropical oils
  • Trans fats — Partially hydrogenated oils (now banned in many countries)
  • Genetics — Familial hypercholesterolemia causes very high LDL
  • Obesity
  • Sedentary lifestyle

How to Lower LDL

  • Reduce saturated fat intake
  • Increase soluble fiber — Oats, beans, fruits
  • Plant sterols and stanols
  • Regular exercise
  • Medications — Statins are highly effective when lifestyle changes aren't enough

Related Biomarkers

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