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GLOSSARY

Red Blood Cells (RBC / Erythrocytes)

Cells that carry oxygen throughout your body. Low counts indicate anemia; high counts may suggest dehydration or other conditions.

What are Red Blood Cells?

Red blood cells (RBCs), also called erythrocytes, are the most abundant cells in your blood. Their primary function is carrying oxygen from your lungs to every tissue in your body and returning carbon dioxide for exhalation.

RBCs contain hemoglobin, the iron-rich protein that binds oxygen. A healthy adult has about 4โ€“6 million RBCs per microliter of blood.

Normal Ranges

GroupRBC Count
Adult men4.5โ€“5.5 million/ยตL
Adult women4.0โ€“5.0 million/ยตL

Why It Matters

Anemia Detection

Low RBC count indicates anemia โ€” insufficient oxygen-carrying capacity. This causes fatigue, weakness, and shortness of breath.

Polycythemia Detection

High RBC count (polycythemia) thickens blood, increasing clot risk. Causes include dehydration, lung disease, and bone marrow disorders.

Overall Health Assessment

RBC count is part of the complete blood count (CBC), one of the most common and informative blood tests.

Low RBC Count (Anemia)

Causes include:

  • Iron, B12, or folate deficiency
  • Chronic disease
  • Blood loss
  • Bone marrow problems
  • Kidney disease (reduced EPO production)

High RBC Count (Polycythemia)

Causes include:

  • Dehydration (most common)
  • Chronic hypoxia (lung disease, high altitude, smoking)
  • Polycythemia vera (bone marrow disorder)
  • EPO-producing tumors

RBC Indices

The CBC includes related measurements:

  • MCV โ€” Average cell size
  • MCH โ€” Average hemoglobin per cell
  • MCHC โ€” Hemoglobin concentration
  • Hematocrit โ€” Percentage of blood volume

Related Biomarkers

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